Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

S23 vs YK-11

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

S23YK-11
Evidence 3/10 3/10
ClassSARMSARM
SummaryS23 is a synthetic selective androgen receptor modulator (SARM) — not a peptide — studied only in rodents as a male contraceptive candidate. There are no human trials, and it is an unapproved drug banned in sport.YK-11 is a synthetic steroidal SARM marketed for muscle growth, but its claimed human benefits rest entirely on cell-culture data — there are no human trials, and it is an unapproved drug banned in sport.
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S23

S23 is a lab-made drug in a family called SARMs (selective androgen receptor modulators — molecules that switch on the same cell "docking points" as testosterone, but only in certain tissues). It is not a peptide. The idea behind it was to build up muscle and bone while having relatively little…

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YK-11

YK-11 is a lab-made compound sold as a SARM (selective androgen receptor modulator — a drug designed to switch on the body's muscle-building signals) and pitched as a way to add muscle. The marketing aside, it is not a peptide. It is a steroid-style molecule built on a 19-norandrostane backbone (a…

Read the full evidence-graded YK-11 profile →

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