<?xml version="1.0" encoding="UTF-8"?><rss version="2.0"><channel><title>Compound Codex</title><description>Evidence-first peptide science, no hype.</description><link>https://www.compoundcodex.com/</link><item><title>5-Amino-1MQ</title><link>https://www.compoundcodex.com/posts/5-amino-1mq/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/5-amino-1mq/</guid><description>A small-molecule NNMT inhibitor (not a peptide) studied for obesity and metabolic disease. The promising data are entirely in mice; there is no verifiable human trial and no approval.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Adipotide (FTPP)</title><link>https://www.compoundcodex.com/posts/adipotide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/adipotide/</guid><description>A pro-apoptotic peptidomimetic that kills the blood vessels feeding white fat. It produced striking fat loss in obese mice and monkeys, but never cleared safety into meaningful human testing — the lone human trial enrolled four patients and reported no results.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>AICAR</title><link>https://www.compoundcodex.com/posts/aicar/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/aicar/</guid><description>AICAR (acadesine) is a small-molecule AMPK activator — not a peptide — famous for making sedentary mice run farther, but with no credible human evidence for endurance, fat loss, or longevity. It is an unapproved experimental drug, banned in sport at all times.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Amycretin</title><link>https://www.compoundcodex.com/posts/amycretin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/amycretin/</guid><description>An investigational single-molecule GLP-1 and amylin receptor agonist from Novo Nordisk with eye-catching early-phase weight-loss data, but no completed Phase 3 trials and no approval anywhere.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Anastrozole (Arimidex)</title><link>https://www.compoundcodex.com/posts/anastrozole/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/anastrozole/</guid><description>Anastrozole is a non-steroidal aromatase inhibitor — a prescription breast-cancer drug, not a peptide — with strong trial evidence in postmenopausal women and a separate, unstudied off-label use by men to suppress estrogen. It is banned in sport at all times.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Boldenone (Equipoise)</title><link>https://www.compoundcodex.com/posts/boldenone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/boldenone/</guid><description>Boldenone is an injectable anabolic-androgenic steroid (a synthetic derivative of testosterone), not a peptide. Its only sanctioned use today is veterinary; there is no modern human clinical evidence supporting its physique or performance claims.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>CagriSema</title><link>https://www.compoundcodex.com/posts/cagrisema/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/cagrisema/</guid><description>An investigational once-weekly fixed combination of cagrilintide (an amylin analog) plus semaglutide (a GLP-1 drug) with large peer-reviewed Phase 3 weight-loss data, but no approval yet and a failed head-to-head against tirzepatide.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Clenbuterol</title><link>https://www.compoundcodex.com/posts/clenbuterol/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/clenbuterol/</guid><description>Clenbuterol is a long-acting beta-2 adrenergic agonist (a bronchodilator and livestock &apos;repartitioning&apos; agent) used off-label for fat loss — never FDA-approved for humans, banned in sport as an anabolic agent, and notable for serious cardiac and electrolyte toxicity. It is not a steroid and not a peptide.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Clomiphene (Clomid)</title><link>https://www.compoundcodex.com/posts/clomiphene/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/clomiphene/</guid><description>Clomiphene is a selective estrogen receptor modulator (SERM), not a peptide, with strong human evidence that it raises testosterone in hypogonadal men while preserving fertility; male use is off-label, it is prescription-only, and it is banned in sport at all times.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Desmopressin (DDAVP)</title><link>https://www.compoundcodex.com/posts/desmopressin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/desmopressin/</guid><description>Desmopressin is an approved synthetic vasopressin analog with strong human evidence for diabetes insipidus and certain bleeding disorders; its biohacking use as a memory enhancer is unsupported and carries a real risk of dangerous low sodium.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Dihexa</title><link>https://www.compoundcodex.com/posts/dihexa/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/dihexa/</guid><description>An angiotensin IV-derived oligopeptide studied in animals for synaptogenesis and cognition; it has never been tested in humans, and its foundational mechanism paper was retracted in 2025.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>DNP (2,4-Dinitrophenol)</title><link>https://www.compoundcodex.com/posts/dnp/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/dnp/</guid><description>DNP is a synthetic mitochondrial uncoupler sold illegally as a &apos;fat burner&apos; — never FDA-approved for human use, with no antidote and a long record of deaths. It is not a peptide and not a steroid.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Drostanolone (Masteron)</title><link>https://www.compoundcodex.com/posts/drostanolone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/drostanolone/</guid><description>Drostanolone is an injectable, DHT-derived anabolic-androgenic steroid once approved as a palliative breast-cancer drug. Its bodybuilding reputation for &apos;hardening&apos; and &apos;dryness&apos; has no controlled human evidence, and it carries the full androgen-class risk profile.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Ecnoglutide</title><link>https://www.compoundcodex.com/posts/ecnoglutide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/ecnoglutide/</guid><description>A long-acting, cAMP-biased GLP-1 receptor agonist approved in China for type 2 diabetes and weight management, with genuine peer-reviewed Phase 3 data that is still confined to Chinese populations and not FDA-approved.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Enclomiphene</title><link>https://www.compoundcodex.com/posts/enclomiphene/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/enclomiphene/</guid><description>Enclomiphene is the anti-estrogenic isomer of clomiphene — a selective estrogen receptor modulator (SERM), not a peptide. Human trials consistently show it raises testosterone while preserving fertility, but it is NOT FDA-approved for any use, is available only via off-label compounding, and is banned in sport at all times.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Exemestane (Aromasin)</title><link>https://www.compoundcodex.com/posts/exemestane/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/exemestane/</guid><description>Exemestane is an oral, steroidal third-generation aromatase inhibitor — an FDA-approved breast-cancer drug, not a peptide. Bodybuilders use it off-label to suppress estrogen, an unapproved and unstudied practice that is banned in sport (WADA S4) and can be genuinely harmful when estrogen is crashed.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Fluoxymesterone (Halotestin)</title><link>https://www.compoundcodex.com/posts/fluoxymesterone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/fluoxymesterone/</guid><description>Fluoxymesterone is an oral 17α-alkylated anabolic-androgenic steroid (not a peptide), once FDA-approved for hypogonadism and breast-cancer palliation but now largely obsolete. Its strongest, best-documented human data concern liver injury rather than benefit, and non-medical use is illegal and banned in sport.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Follistatin 344</title><link>https://www.compoundcodex.com/posts/follistatin-344/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/follistatin-344/</guid><description>A myostatin/activin-pathway antagonist that is biologically real but clinically unproven; its only legitimate human testing was tiny early-phase gene therapy in muscular dystrophy, with no human evidence for muscle-building or weight loss, no regulatory approval, and a permanent WADA ban.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Glutathione</title><link>https://www.compoundcodex.com/posts/glutathione/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/glutathione/</guid><description>Glutathione is the body&apos;s main intracellular antioxidant tripeptide. Oral dosing reliably raises body stores in humans, but the popular IV skin-lightening, anti-aging, and performance claims are unproven — and the injectable cosmetic market carries the real risk.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>HCG (Human Chorionic Gonadotropin)</title><link>https://www.compoundcodex.com/posts/hcg/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/hcg/</guid><description>HCG is a glycoprotein gonadotropin that mimics luteinizing hormone, with strong human evidence for fertility and hypogonadism uses and a formal FDA disclaimer against the discredited &apos;hCG diet&apos; for weight loss.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Humanin</title><link>https://www.compoundcodex.com/posts/humanin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/humanin/</guid><description>Humanin is a mitochondrial-derived peptide with interesting cell and animal data in aging and neuroprotection, but the human evidence is entirely observational — no interventional trial of administered humanin in people exists. It&apos;s unapproved and effectively uncharacterized for safety in humans.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>IGF-1 DES</title><link>https://www.compoundcodex.com/posts/igf-1-des/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/igf-1-des/</guid><description>A naturally occurring, shorter and more potent variant of IGF-1 with anabolic effects in rodents and cell culture, but no human trials for its marketed uses; not approved anywhere and banned in sport.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Insulin</title><link>https://www.compoundcodex.com/posts/insulin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/insulin/</guid><description>Insulin is a 51-amino-acid peptide hormone and one of medicine&apos;s most life-saving drugs for diabetes — but as a performance/anabolic agent in healthy people it has no good efficacy evidence and the highest acute lethality risk of common PEDs.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Letrozole (Femara)</title><link>https://www.compoundcodex.com/posts/letrozole/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/letrozole/</guid><description>Letrozole is an oral, nonsteroidal third-generation aromatase inhibitor — an FDA-approved breast-cancer and (off-label) fertility drug, not a peptide. Bodybuilders use it off-label to suppress estrogen, an unapproved and unstudied practice that is banned in sport (WADA S4) and can be genuinely harmful when estrogen is crashed.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>LGD-3303</title><link>https://www.compoundcodex.com/posts/lgd-3303/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/lgd-3303/</guid><description>LGD-3303 is a nonsteroidal selective androgen receptor modulator (SARM), not a peptide. Its evidence is preclinical (rodent) only — there are no human trials. It is an unapproved research chemical and is banned at all times in sport.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Liothyronine (T3, Cytomel)</title><link>https://www.compoundcodex.com/posts/liothyronine/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/liothyronine/</guid><description>Liothyronine is synthetic T3 thyroid hormone — an FDA-approved prescription drug (not a peptide), misused off-label as a fat-loss agent. Properly dosed and monitored it looks safe; the danger is dose-driven thyrotoxicosis from unsupervised overdose.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Mesterolone (Proviron)</title><link>https://www.compoundcodex.com/posts/mesterolone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/mesterolone/</guid><description>Mesterolone is an oral, DHT-derived anabolic-androgenic steroid once sold abroad for male hypogonadism and idiopathic infertility. Controlled human trials for its two historic uses (fertility, mood) are negative or unconvincing, and its performance &apos;anti-estrogen&apos; reputation has no strong human evidence.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Methandrostenolone (Dianabol)</title><link>https://www.compoundcodex.com/posts/methandrostenolone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/methandrostenolone/</guid><description>An oral 17α-alkylated anabolic-androgenic steroid (not a peptide) with real but modest controlled-trial evidence for gains in body weight and lean mass; it is a Schedule III controlled substance with no current US medical use and well-documented liver, cardiovascular, and hormonal harms.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Methasterone (Superdrol)</title><link>https://www.compoundcodex.com/posts/methasterone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/methasterone/</guid><description>Methasterone is an oral 17α-alkylated anabolic-androgenic steroid (a 17α-methyl version of drostanolone), never an approved medicine; its only robust human evidence is harm — severe cholestatic liver injury — not efficacy.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Methenolone (Primobolan)</title><link>https://www.compoundcodex.com/posts/methenolone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/methenolone/</guid><description>A DHT-derived anabolic-androgenic steroid once used medically for bone-marrow-failure anemias and historically studied in breast cancer; its &apos;mild and safe&apos; bodybuilding reputation rests on lore, not controlled performance trials.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>MGF (Mechano Growth Factor)</title><link>https://www.compoundcodex.com/posts/mgf/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/mgf/</guid><description>MGF is a muscle-derived splice variant of IGF-1 with a plausible repair-signaling mechanism, but no human drug trials exist — the evidence is animal and cell-culture only, and it is banned in sport.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Nandrolone (Deca-Durabolin)</title><link>https://www.compoundcodex.com/posts/nandrolone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/nandrolone/</guid><description>Nandrolone is an injectable anabolic-androgenic steroid (not a peptide) with high-quality trial evidence that it builds lean mass in catabolic illness, but weaker evidence for strength or functional gains and real androgenic, hormonal, and cardiovascular risks.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Orforglipron</title><link>https://www.compoundcodex.com/posts/orforglipron/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/orforglipron/</guid><description>An oral, non-peptide (small-molecule) GLP-1 receptor agonist, FDA-approved in April 2026 as Foundayo for chronic weight management. It is a once-daily pill with no food or timing restrictions — not a peptide, and not an injectable.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Oxymetholone (Anadrol)</title><link>https://www.compoundcodex.com/posts/oxymetholone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/oxymetholone/</guid><description>Oxymetholone is a potent oral anabolic-androgenic steroid (not a peptide) with genuine controlled-trial support in wasting illness, but it carries serious, well-documented liver, lipid, and hormonal risks.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Raloxifene (Evista)</title><link>https://www.compoundcodex.com/posts/raloxifene/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/raloxifene/</guid><description>Raloxifene is a selective estrogen receptor modulator (SERM) — an FDA-approved postmenopausal osteoporosis and breast-cancer-risk-reduction drug, not a peptide. Its defining serious risks are blood clots and fatal stroke; it is banned in sport at all times (WADA S4.2).</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>SLU-PP-332</title><link>https://www.compoundcodex.com/posts/slu-pp-332/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/slu-pp-332/</guid><description>SLU-PP-332 is a synthetic small-molecule pan-agonist of the estrogen-related receptors (ERRα/β/γ) studied as an &apos;exercise mimetic&apos; — not a peptide, and animal-stage only with no human data.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>SNAP-8 (Acetyl Octapeptide-3)</title><link>https://www.compoundcodex.com/posts/snap-8/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/snap-8/</guid><description>SNAP-8 is a topical cosmetic peptide sold as a needle-free &quot;Botox-like&quot; wrinkle treatment. The wrinkle-reduction figures trace to manufacturer data, and skin-penetration problems undercut the core mechanism.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Somatropin (HGH)</title><link>https://www.compoundcodex.com/posts/somatropin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/somatropin/</guid><description>Recombinant human growth hormone — a protein hormone with strong evidence in true GH deficiency and specific medical conditions, but only small body-composition changes and no proven performance benefit in healthy adults. Non-medical distribution is a federal felony.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Stanozolol (Winstrol)</title><link>https://www.compoundcodex.com/posts/stanozolol/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/stanozolol/</guid><description>Stanozolol is an oral/injectable anabolic-androgenic steroid with a famous doping history; its physique reputation rests on weak evidence, while its harmful effects on lipids and the liver are robustly documented.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Tamoxifen (Nolvadex)</title><link>https://www.compoundcodex.com/posts/tamoxifen/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/tamoxifen/</guid><description>Tamoxifen is a selective estrogen receptor modulator (SERM) — an FDA-approved breast-cancer drug with one of the strongest evidence bases in oncology, not a peptide. Anabolic-steroid users take it off-label to blunt gynecomastia and attempt testosterone &apos;restart,&apos; an unstudied practice that is banned in sport (WADA S4.2) and not without real risk.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Tesofensine</title><link>https://www.compoundcodex.com/posts/tesofensine/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/tesofensine/</guid><description>Tesofensine is an investigational oral triple monoamine (noradrenaline/dopamine/serotonin) reuptake inhibitor studied for obesity. It is a small molecule, not a peptide, and is not approved by any major regulator. It is banned in sport as a stimulant.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Testosterone</title><link>https://www.compoundcodex.com/posts/testosterone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/testosterone/</guid><description>Testosterone is the principal human androgen and the prototypical anabolic-androgenic steroid (AAS) — not a peptide — with strong, reproducible human evidence for dose-dependent muscle and strength gains, FDA approval only for confirmed hypogonadism, Schedule III control, and real cardiovascular, hematologic, and hormonal safety signals.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Thymalin</title><link>https://www.compoundcodex.com/posts/thymalin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/thymalin/</guid><description>A Russian thymus-extract peptide preparation studied for immune modulation; the human data is real but thin, small, mostly non-blinded, from one research lineage, and unreplicated outside Russia.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Trenbolone</title><link>https://www.compoundcodex.com/posts/trenbolone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/trenbolone/</guid><description>Trenbolone is a potent injectable anabolic-androgenic steroid — never a peptide — with no human efficacy trials, an FDA-approved use only as a cattle growth-promoting implant, and serious androgenic, cardiovascular, and hormonal risks.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Turinabol (Oral Turinabol)</title><link>https://www.compoundcodex.com/posts/turinabol/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/turinabol/</guid><description>Turinabol is an orally active 17α-alkylated anabolic-androgenic steroid — the signature drug of East Germany&apos;s state doping program — with no modern controlled human efficacy trials and the full risk profile of an oral AAS.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>VIP (Vasoactive Intestinal Peptide)</title><link>https://www.compoundcodex.com/posts/vip/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/vip/</guid><description>A natural anti-inflammatory neuropeptide with no FDA-approved product; its largest rigorous human trial was negative, and the intranasal &apos;CIRS&apos; and biohacking uses sold online rest on a single research group&apos;s uncontrolled reports.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>VK2735 (Viking)</title><link>https://www.compoundcodex.com/posts/vk2735/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/vk2735/</guid><description>VK2735 is an investigational dual GLP-1/GIP receptor agonist from Viking Therapeutics being studied for obesity and metabolic disease. Phase 2 data are promising but it is not approved anywhere, and long-term safety is unknown.</description><pubDate>Thu, 04 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Andarine (S4)</title><link>https://www.compoundcodex.com/posts/andarine/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/andarine/</guid><description>A non-steroidal SARM with tissue-selective anabolic activity in rodents, but no completed human efficacy trials; clinical development was halted over vision side effects.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Cardarine (GW-501516)</title><link>https://www.compoundcodex.com/posts/cardarine/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/cardarine/</guid><description>Cardarine (GW-501516) is a synthetic PPARδ agonist, not a peptide or SARM, abandoned in development after rodent studies showed multi-organ cancer; it is banned in sport and has no approved human use.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Ligandrol (LGD-4033)</title><link>https://www.compoundcodex.com/posts/lgd-4033/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/lgd-4033/</guid><description>Ligandrol (LGD-4033) is a nonsteroidal selective androgen receptor modulator (SARM), not a peptide. Its only real human data is a single 3-week Phase 1 trial; it is an unapproved drug, illegal to sell as a supplement, and banned in sport.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Methylene Blue</title><link>https://www.compoundcodex.com/posts/methylene-blue/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/methylene-blue/</guid><description>A synthetic redox dye with one strong, FDA-approved use (treating methemoglobinemia) and a long list of popular biohacking claims that human evidence does not support.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>NMN</title><link>https://www.compoundcodex.com/posts/nmn/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/nmn/</guid><description>NMN is a small-molecule NAD+ precursor that reliably raises blood NAD+ levels in humans, but its marketed anti-aging and metabolic benefits remain preliminary and surrogate-based.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Ostarine (MK-2866)</title><link>https://www.compoundcodex.com/posts/ostarine/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/ostarine/</guid><description>Ostarine is an investigational selective androgen receptor modulator (SARM) — not a peptide — with real but limited human evidence for lean-mass effects, no regulatory approval anywhere, and documented liver-injury and hormone-suppression signals.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Oxandrolone (Anavar)</title><link>https://www.compoundcodex.com/posts/oxandrolone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/oxandrolone/</guid><description>Oxandrolone is an oral anabolic-androgenic steroid with genuine clinical trial support in catabolic illness (severe burns, HIV wasting, Turner syndrome), but its &apos;mild and safe&apos; reputation is marketing, not evidence.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Testolone (RAD-140)</title><link>https://www.compoundcodex.com/posts/rad-140/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/rad-140/</guid><description>An investigational, non-approved selective androgen receptor modulator (SARM) with no published human efficacy evidence for fitness use, a documented serious liver-injury case, and prohibited status in sport.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>S23</title><link>https://www.compoundcodex.com/posts/s23/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/s23/</guid><description>S23 is a synthetic selective androgen receptor modulator (SARM) — not a peptide — studied only in rodents as a male contraceptive candidate. There are no human trials, and it is an unapproved drug banned in sport.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Stenabolic (SR9009)</title><link>https://www.compoundcodex.com/posts/sr9009/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/sr9009/</guid><description>SR9009 is a synthetic REV-ERB agonist (not a peptide, not a SARM) with intriguing mouse metabolic data but no credible human evidence, poor oral bioavailability, and documented off-target activity. Unapproved drug, banned in sport at all times.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Turkesterone</title><link>https://www.compoundcodex.com/posts/turkesterone/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/turkesterone/</guid><description>An ecdysteroid (plant/insect steroid) marketed as a &apos;natural anabolic,&apos; but with essentially no direct human evidence for muscle or strength benefits — the supporting science is mostly about the related compound 20-hydroxyecdysone and is itself weak and mixed.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>YK-11</title><link>https://www.compoundcodex.com/posts/yk-11/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/yk-11/</guid><description>YK-11 is a synthetic steroidal SARM marketed for muscle growth, but its claimed human benefits rest entirely on cell-culture data — there are no human trials, and it is an unapproved drug banned in sport.</description><pubDate>Wed, 03 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Afamelanotide (Melanotan-1): An Approved Orphan Drug With Modest, Single-Sponsor Evidence</title><link>https://www.compoundcodex.com/posts/afamelanotide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/afamelanotide/</guid><description>Afamelanotide is an FDA- and EMA-approved implant for a rare light-sensitivity disease. The trial evidence is real but modest, and it is not the gray-market tanning drug.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>ARA-290 (Cibinetide): A Non-Blood-Building EPO Fragment With Early, Conflicted Human Data</title><link>https://www.compoundcodex.com/posts/ara-290/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/ara-290/</guid><description>ARA-290 is an investigational EPO-derived peptide studied for nerve injury. Real but small, short, developer-run trials exist — no Phase 3 and no approval.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Argireline (Acetyl Hexapeptide-8): Small Human Trials Behind a &quot;Topical Botox&quot; Claim</title><link>https://www.compoundcodex.com/posts/argireline/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/argireline/</guid><description>Argireline is a topical cosmetic peptide marketed as &quot;Botox in a bottle.&quot; Small human trials are mildly positive, but skin-penetration data undercut the core mechanism.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Cagrilintide: A Long-Acting Amylin Analog with Strong Combination Data and Thin Standalone Evidence</title><link>https://www.compoundcodex.com/posts/cagrilintide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/cagrilintide/</guid><description>Cagrilintide is an investigational once-weekly amylin analog from Novo Nordisk. The robust human data are for the CagriSema combination, not the drug alone.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Cerebrolysin: A Heavily Studied Brain Peptide Whose Best Trials Came Up Short</title><link>https://www.compoundcodex.com/posts/cerebrolysin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/cerebrolysin/</guid><description>Cerebrolysin has more human trial data than most research peptides, yet its largest rigorous stroke trial was neutral and independent reviews find little benefit.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>GHRP-2: A diagnostic peptide with thin therapeutic evidence</title><link>https://www.compoundcodex.com/posts/ghrp-2/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/ghrp-2/</guid><description>GHRP-2 (pralmorelin) provokes a growth hormone pulse. It is an approved diagnostic in Japan, but the human therapeutic and anti-aging evidence is small and old.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>GHRP-6: well-mapped pharmacology, unproven benefits</title><link>https://www.compoundcodex.com/posts/ghrp-6/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/ghrp-6/</guid><description>An old growth-hormone-releasing peptide that reliably raises GH and appetite in humans, but whose marketed muscle, fat-loss, and disease claims lack solid trials.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Gonadorelin: Strong in a Narrow Lane, Unproven for the Popular One</title><link>https://www.compoundcodex.com/posts/gonadorelin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/gonadorelin/</guid><description>Gonadorelin is synthetic GnRH with decades of human data in GnRH-deficiency, but no trial evidence for the TRT-adjunct use that drives its popularity.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Hexarelin: A Potent GH Trigger That Stalled at Early Human Trials</title><link>https://www.compoundcodex.com/posts/hexarelin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/hexarelin/</guid><description>A synthetic ghrelin-mimicking peptide that reliably spikes growth hormone in small studies, but was never approved and is banned in sport.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Kisspeptin-10: A Real Hormone Switch With Thin Human Evidence</title><link>https://www.compoundcodex.com/posts/kisspeptin-10/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/kisspeptin-10/</guid><description>Kisspeptin-10 reliably raises reproductive hormones in short human studies, but the headline fertility and libido results belong to a different molecule, kisspeptin-54.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>KPV: A Promising Anti-Inflammatory Tripeptide With No Human Trials</title><link>https://www.compoundcodex.com/posts/kpv/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/kpv/</guid><description>A three-amino-acid fragment of alpha-MSH with strong anti-inflammatory effects in animal and cell studies, but zero published human trials. Unapproved and gray-market.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Liraglutide (Victoza / Saxenda): An Evidence Review</title><link>https://www.compoundcodex.com/posts/liraglutide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/liraglutide/</guid><description>A once-daily GLP-1 drug with large RCT support for glucose control, weight loss, and lower cardiovascular risk in high-risk type 2 diabetes.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>LL-37: A real human peptide with thin, mostly negative clinical data</title><link>https://www.compoundcodex.com/posts/ll-37/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/ll-37/</guid><description>LL-37 is the body&apos;s only human cathelicidin. As a drug it has small early trials and one larger study that failed its primary endpoint.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Mazdutide: real Phase 3 data, but almost all of it from China</title><link>https://www.compoundcodex.com/posts/mazdutide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/mazdutide/</guid><description>A GLP-1/glucagon dual agonist approved in China for weight loss and diabetes, with genuine RCT evidence that is still sponsor-funded and single-country.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>MK-677 (Ibutamoren): A Lot of Human Data, Little to Show for It</title><link>https://www.compoundcodex.com/posts/mk-677/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/mk-677/</guid><description>MK-677 reliably raises growth hormone and IGF-1, but disease trials failed and one was stopped for a heart-failure signal. Investigational, never approved.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Oxytocin: A Proven Birth Drug, an Unproven &quot;Bonding&quot; Spray</title><link>https://www.compoundcodex.com/posts/oxytocin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/oxytocin/</guid><description>Oxytocin is a strong, evidence-based obstetric medicine by injection. The intranasal &quot;bonding&quot; version sold online is a different story, and the pivotal autism trial was negative.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Setmelanotide (Imcivree): Strong Evidence in Rare Obesity, None Beyond It</title><link>https://www.compoundcodex.com/posts/setmelanotide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/setmelanotide/</guid><description>An FDA-approved peptide for a handful of rare genetic and acquired forms of severe obesity, with no credible evidence for general weight loss.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>SS-31 (Elamipretide): Real human trials, mostly failed endpoints, one narrow approval</title><link>https://www.compoundcodex.com/posts/ss-31/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/ss-31/</guid><description>Elamipretide won a narrow FDA accelerated approval for Barth syndrome in 2025, but its largest trials in myopathy, heart failure, and dry AMD all missed.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Survodutide: Strong Phase 2 data and a first Phase 3 readout, but still investigational</title><link>https://www.compoundcodex.com/posts/survodutide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/survodutide/</guid><description>An investigational GLP-1/glucagon dual agonist with solid placebo-controlled Phase 2 trials and one positive Phase 3 topline, but no approval and no peer-reviewed Phase 3 data.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Thymosin Beta-4: Real Human Trials, But the Best Indication Has Missed Two Phase 3s</title><link>https://www.compoundcodex.com/posts/thymosin-beta-4/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/thymosin-beta-4/</guid><description>Full-length thymosin beta-4 has genuine human trials for eye-surface and wound healing, but the evidence is small, sponsor-driven, and largely missed its primary endpoints.</description><pubDate>Tue, 02 Jun 2026 00:00:00 GMT</pubDate></item><item><title>AOD-9604</title><link>https://www.compoundcodex.com/posts/aod-9604/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/aod-9604/</guid><description>A growth-hormone fragment marketed for fat loss. The human trials were small and short, the pivotal obesity study failed, and development was abandoned. Unapproved as a drug everywhere.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>BPC-157: Big Claims, Almost No Human Evidence</title><link>https://www.compoundcodex.com/posts/bpc-157/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/bpc-157/</guid><description>A synthetic peptide marketed for healing, but human data is limited to a few tiny uncontrolled studies. It is unapproved and banned in sport.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>CJC-1295</title><link>https://www.compoundcodex.com/posts/cjc-1295/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/cjc-1295/</guid><description>A long-acting GHRH analog that raises GH and IGF-1 in short human trials, but has no clinical-outcome data, is not FDA-approved, and is banned in sport.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>DSIP (Delta Sleep-Inducing Peptide)</title><link>https://www.compoundcodex.com/posts/dsip/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/dsip/</guid><description>DSIP is a naturally occurring brain peptide studied for sleep in small, dated trials with mixed results; modern human evidence is essentially absent.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Epitalon (Epithalon): What the Evidence Actually Shows</title><link>https://www.compoundcodex.com/posts/epitalon/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/epitalon/</guid><description>Epitalon is a synthetic pineal tetrapeptide marketed for anti-aging; human data on the peptide itself is sparse, mostly Russian and from a single research lineage, with safety largely uncharacterized.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>GHK-Cu (Copper Peptide): What the Evidence Actually Shows</title><link>https://www.compoundcodex.com/posts/ghk-cu/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/ghk-cu/</guid><description>GHK-Cu is a copper-binding peptide with small, mostly cosmetic-industry skin trials, lots of lab data, and no large independent human RCTs.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>IGF-1 LR3</title><link>https://www.compoundcodex.com/posts/igf-1-lr3/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/igf-1-lr3/</guid><description>A long-acting synthetic IGF-1 analog with anabolic effects in animals and cell culture, but no human trials for its marketed uses; not FDA-approved and banned in sport.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Ipamorelin</title><link>https://www.compoundcodex.com/posts/ipamorelin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/ipamorelin/</guid><description>A selective growth-hormone-releasing peptide with early human safety data but a failed efficacy trial; never approved and banned in sport.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Melanotan II: It Tans, But It&apos;s Unapproved and Carries Real Harms</title><link>https://www.compoundcodex.com/posts/melanotan-2/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/melanotan-2/</guid><description>A synthetic tanning peptide that does something, but is unapproved, unregulated, and tied to serious harms from priapism to melanoma case reports.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>MOTS-c</title><link>https://www.compoundcodex.com/posts/mots-c/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/mots-c/</guid><description>MOTS-c is a mitochondrial peptide with strong rodent metabolic data but no completed, published human efficacy trial. It&apos;s unapproved and WADA-banned.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>PT-141 (Bremelanotide / Vyleesi)</title><link>https://www.compoundcodex.com/posts/pt-141/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/pt-141/</guid><description>An FDA-approved melanocortin agonist for low sexual desire in premenopausal women. Two real Phase 3 trials show a small, genuine benefit for that one use; almost everything else people take it for is unstudied.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Retatrutide</title><link>https://www.compoundcodex.com/posts/retatrutide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/retatrutide/</guid><description>An investigational triple-hormone agonist with striking weight-loss data in trials, but not yet FDA-approved and with no peer-reviewed Phase 3 results.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Selank</title><link>https://www.compoundcodex.com/posts/selank/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/selank/</guid><description>A Russian-developed anxiolytic peptide approved in Russia but unproven by Western standards; human trials are small, early, and single-country.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Semaglutide (Ozempic / Wegovy): An Evidence Review</title><link>https://www.compoundcodex.com/posts/semaglutide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/semaglutide/</guid><description>A GLP-1 drug with strong RCT evidence for weight loss, glucose control, and cutting cardiovascular events in high-risk patients.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Semax</title><link>https://www.compoundcodex.com/posts/semax/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/semax/</guid><description>A Russian-approved nootropic/neuroprotective peptide whose human evidence is real but small, mostly Russian-language, and methodologically thin.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Sermorelin</title><link>https://www.compoundcodex.com/posts/sermorelin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/sermorelin/</guid><description>Sermorelin is a synthetic GHRH fragment that nudges the pituitary to release growth hormone; human data is old and thin, with no modern anti-aging RCTs.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>TB-500 (Thymosin Beta-4 Fragment): What the Evidence Actually Shows</title><link>https://www.compoundcodex.com/posts/tb-500/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/tb-500/</guid><description>TB-500 is a synthetic thymosin beta-4 fragment marketed for healing, but human data on the fragment itself is essentially absent and the supporting research is animal-only.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Tesamorelin (Egrifta): An Evidence-Graded Profile</title><link>https://www.compoundcodex.com/posts/tesamorelin/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/tesamorelin/</guid><description>Tesamorelin is an FDA-approved GHRH analogue with solid RCT evidence for shrinking visceral fat in HIV-associated lipodystrophy, but little proof outside that group.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Thymosin Alpha-1</title><link>https://www.compoundcodex.com/posts/thymosin-alpha-1/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/thymosin-alpha-1/</guid><description>A thymus-derived immune-modulating peptide with real but mixed human trial data: helpful in hepatitis B, but negative in the largest sepsis trial.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item><item><title>Tirzepatide (Mounjaro / Zepbound)</title><link>https://www.compoundcodex.com/posts/tirzepatide/</link><guid isPermaLink="true">https://www.compoundcodex.com/posts/tirzepatide/</guid><description>A dual GIP/GLP-1 receptor agonist with strong RCT evidence for type 2 diabetes, weight loss, and sleep apnea; GI side effects are common.</description><pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate></item></channel></rss>