Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · Anabolic steroid

Mesterolone vs Methasterone

Both are anabolic steroid compounds. Here's how they line up on the evidence — graded the same way.

MesteroloneMethasterone
Evidence 1/10 3/10
ClassAnabolic steroidAnabolic steroid
SummaryMesterolone is an oral, DHT-derived anabolic-androgenic steroid once sold abroad for male hypogonadism and idiopathic infertility. Controlled human trials for its two historic uses (fertility, mood) are negative or unconvincing, and its performance 'anti-estrogen' reputation has no strong human evidence.Methasterone is an oral 17α-alkylated anabolic-androgenic steroid (a 17α-methyl version of drostanolone), never an approved medicine; its only robust human evidence is harm — severe cholestatic liver injury — not efficacy.
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Mesterolone

Mesterolone, almost always sold under the brand name Proviron, is a man-made oral steroid. More precisely, it's an anabolic-androgenic steroid (AAS) — a synthetic relative of the male hormone dihydrotestosterone (DHT). It's an androgen (a male-hormone-type drug), not a peptide and not a SARM.…

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Methasterone

Methasterone — most people know it by the designer-supplement name Superdrol, and chemists call it methyldrostanolone — is a man-made anabolic-androgenic steroid (AAS), not a peptide. It is an oral steroid built on a dihydrotestosterone backbone, with a chemical tweak called 17α-alkylation that…

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