Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

Ligandrol vs YK-11

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

LigandrolYK-11
Evidence 7/10 3/10
ClassSARMSARM
SummaryLigandrol (LGD-4033) is a nonsteroidal selective androgen receptor modulator (SARM), not a peptide. Its only real human data is a single 3-week Phase 1 trial; it is an unapproved drug, illegal to sell as a supplement, and banned in sport.YK-11 is a synthetic steroidal SARM marketed for muscle growth, but its claimed human benefits rest entirely on cell-culture data — there are no human trials, and it is an unapproved drug banned in sport.
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Ligandrol

Ligandrol (LGD-4033) is a SARM (selective androgen receptor modulator — a drug that turns on the same cell switch as testosterone, but only in some tissues). Importantly, it is a small lab-made molecule, not a peptide. It is sold widely online and is popular in fitness circles, where it is pitched…

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YK-11

YK-11 is a lab-made compound sold as a SARM (selective androgen receptor modulator — a drug designed to switch on the body's muscle-building signals) and pitched as a way to add muscle. The marketing aside, it is not a peptide. It is a steroid-style molecule built on a 19-norandrostane backbone (a…

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