Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

Ligandrol vs Testolone

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

LigandrolTestolone
Evidence 7/10 3/10
ClassSARMSARM
SummaryLigandrol (LGD-4033) is a nonsteroidal selective androgen receptor modulator (SARM), not a peptide. Its only real human data is a single 3-week Phase 1 trial; it is an unapproved drug, illegal to sell as a supplement, and banned in sport.An investigational, non-approved selective androgen receptor modulator (SARM) with no published human efficacy evidence for fitness use, a documented serious liver-injury case, and prohibited status in sport.
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Ligandrol

Ligandrol (LGD-4033) is a SARM (selective androgen receptor modulator — a drug that turns on the same cell switch as testosterone, but only in some tissues). Importantly, it is a small lab-made molecule, not a peptide. It is sold widely online and is popular in fitness circles, where it is pitched…

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Testolone

Testolone (RAD-140) is a selective androgen receptor modulator, or SARM (a drug that switches on the body's testosterone-sensing receptor in a targeted way). It is a small molecule made in a lab — not a peptide, and not an anabolic steroid. It was created as an experimental drug, was never approved…

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