Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

LGD-3303 vs YK-11

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

LGD-3303YK-11
Evidence 3/10 3/10
ClassSARMSARM
SummaryLGD-3303 is a nonsteroidal selective androgen receptor modulator (SARM), not a peptide. Its evidence is preclinical (rodent and equine) only — there are no human trials. It is an unapproved research chemical and is banned at all times in sport.YK-11 is a synthetic steroidal SARM marketed for muscle growth, but its claimed human benefits rest entirely on cell-culture data — there are no human trials, and it is an unapproved drug banned in sport.
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LGD-3303

LGD-3303 is a SARM — a selective androgen receptor modulator (a lab-made molecule that switches on the body's androgen, or male-hormone, receptors in some tissues but not others). It is not a peptide, and it is not a steroid. It came out of the same Ligand Pharmaceuticals research program as…

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YK-11

YK-11 is a lab-made compound sold as a SARM (selective androgen receptor modulator — a drug designed to switch on the body's muscle-building signals) and pitched as a way to add muscle. The marketing aside, it is not a peptide. It is a steroid-style molecule built on a 19-norandrostane backbone (a…

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