Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

LGD-3303 vs Testolone

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

LGD-3303Testolone
Evidence 3/10 3/10
ClassSARMSARM
SummaryLGD-3303 is a nonsteroidal selective androgen receptor modulator (SARM), not a peptide. Its evidence is preclinical (rodent and equine) only — there are no human trials. It is an unapproved research chemical and is banned at all times in sport.An investigational, non-approved selective androgen receptor modulator (SARM) with no published human efficacy evidence for fitness use, a documented serious liver-injury case, and prohibited status in sport.
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LGD-3303

LGD-3303 is a SARM — a selective androgen receptor modulator (a lab-made molecule that switches on the body's androgen, or male-hormone, receptors in some tissues but not others). It is not a peptide, and it is not a steroid. It came out of the same Ligand Pharmaceuticals research program as…

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Testolone

Testolone (RAD-140) is a selective androgen receptor modulator, or SARM (a drug that switches on the body's testosterone-sensing receptor in a targeted way). It is a small molecule made in a lab — not a peptide, and not an anabolic steroid. It was created as an experimental drug, was never approved…

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