Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

LGD-3303 vs Ostarine

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

LGD-3303Ostarine
Evidence 3/10 7/10
ClassSARMSARM
SummaryLGD-3303 is a nonsteroidal selective androgen receptor modulator (SARM), not a peptide. Its evidence is preclinical (rodent and equine) only — there are no human trials. It is an unapproved research chemical and is banned at all times in sport.Ostarine is an investigational selective androgen receptor modulator (SARM) — not a peptide — with real but limited human evidence for lean-mass effects, no regulatory approval anywhere, and documented liver-injury and hormone-suppression signals.
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LGD-3303

LGD-3303 is a SARM — a selective androgen receptor modulator (a lab-made molecule that switches on the body's androgen, or male-hormone, receptors in some tissues but not others). It is not a peptide, and it is not a steroid. It came out of the same Ligand Pharmaceuticals research program as…

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Ostarine

Ostarine (also called MK-2866 or enobosarm) is a selective androgen receptor modulator (a compound designed to act like a muscle-building hormone in some tissues but not others). It is often — and wrongly — sold online as a "safer steroid alternative" for building muscle. It is not a peptide, and…

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