Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

LGD-3303 vs Ligandrol

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

LGD-3303Ligandrol
Evidence 3/10 7/10
ClassSARMSARM
SummaryLGD-3303 is a nonsteroidal selective androgen receptor modulator (SARM), not a peptide. Its evidence is preclinical (rodent and equine) only — there are no human trials. It is an unapproved research chemical and is banned at all times in sport.Ligandrol (LGD-4033) is a nonsteroidal selective androgen receptor modulator (SARM), not a peptide. Its only real human data is a single 3-week Phase 1 trial; it is an unapproved drug, illegal to sell as a supplement, and banned in sport.
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LGD-3303

LGD-3303 is a SARM — a selective androgen receptor modulator (a lab-made molecule that switches on the body's androgen, or male-hormone, receptors in some tissues but not others). It is not a peptide, and it is not a steroid. It came out of the same Ligand Pharmaceuticals research program as…

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Ligandrol

Ligandrol (LGD-4033) is a SARM (selective androgen receptor modulator — a drug that turns on the same cell switch as testosterone, but only in some tissues). Importantly, it is a small lab-made molecule, not a peptide. It is sold widely online and is popular in fitness circles, where it is pitched…

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