Compare · GH secretagogue
Ipamorelin vs Tesamorelin
Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.
| Ipamorelin | Tesamorelin | |
|---|---|---|
| Evidence | 6/10 | 8/10 |
| Class | GH secretagogue | GH secretagogue |
| Summary | A selective growth-hormone-releasing peptide with early human safety data but a failed efficacy trial; never approved and banned in sport. | Tesamorelin is an FDA-approved GHRH analogue with solid RCT evidence for shrinking visceral fat in HIV-associated lipodystrophy, but little proof outside that group. |
| Full profile → | Full profile → |
Ipamorelin
Ipamorelin is a lab-made peptide (a short chain of amino acids, the building blocks of proteins) that briefly nudges up your body's growth hormone (GH). It has been tested in people, but the one trial that checked for a real-world health benefit didn't pan out, and it has never been approved for…
Tesamorelin
Tesamorelin, sold as Egrifta, is one of the few peptides in this space that actually has strong, FDA-grade human evidence behind it. The catch: almost all of that evidence comes from one specific group of patients. And a lot of the way the compound gets marketed elsewhere goes well past what those…