Compare · GH secretagogue
Ipamorelin vs Sermorelin
Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.
| Ipamorelin | Sermorelin | |
|---|---|---|
| Evidence | 6/10 | 8/10 |
| Class | GH secretagogue | GH secretagogue |
| Summary | A selective growth-hormone-releasing peptide with early human safety data but a failed efficacy trial; never approved and banned in sport. | Sermorelin is a synthetic GHRH fragment that nudges the pituitary to release growth hormone; human data is old and thin, with no modern anti-aging RCTs. |
| Full profile → | Full profile → |
Ipamorelin
Ipamorelin is a lab-made peptide (a short chain of amino acids, the building blocks of proteins) that briefly nudges up your body's growth hormone (GH). It has been tested in people, but the one trial that checked for a real-world health benefit didn't pan out, and it has never been approved for…
Sermorelin
Sermorelin is one of the oldest peptides in the "growth hormone" group, and unlike most of its cousins it actually held FDA approval at one point. People often lean on that history to suggest it does more than the evidence really backs up.