Compare · Growth factor
IGF-1 DES vs MGF
Both are growth factor compounds. Here's how they line up on the evidence — graded the same way.
| IGF-1 DES | MGF | |
|---|---|---|
| Evidence | Animal only | Animal only |
| Class | Growth factor | Growth factor |
| Summary | A naturally occurring, shorter and more potent variant of IGF-1 with anabolic effects in rodents and cell culture, but no human trials for its marketed uses; not approved anywhere and banned in sport. | MGF is a muscle-derived splice variant of IGF-1 with a plausible repair-signaling mechanism, but no human drug trials exist — the evidence is animal and cell-culture only, and it is banned in sport. |
| Full profile → | Full profile → |
IGF-1 DES
IGF-1 DES is a real, well-characterized variant of insulin-like growth factor 1 (IGF-1) that is shorter than the native hormone and more potent in the lab. It is sold "for research use only" and promoted for muscle and fat loss, but no human trial supports any of those uses.
MGF
MGF (mechano growth factor) is a muscle-derived splice variant of insulin-like growth factor 1. It has a genuinely interesting biology and a plausible role in muscle repair, but it is sold as a research chemical (often as a PEGylated form, PEG-MGF) on the strength of mechanisms and animal work —…