Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · GH secretagogue

Hexarelin vs Tesamorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

HexarelinTesamorelin
Evidence 6/10 8/10
ClassGH secretagogueGH secretagogue
SummaryA synthetic ghrelin-mimicking peptide that reliably spikes growth hormone in small studies, but was never approved and is banned in sport.Tesamorelin is an FDA-approved GHRH analogue with solid RCT evidence for shrinking visceral fat in HIV-associated lipodystrophy, but little proof outside that group.
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Hexarelin

Hexarelin is a lab-made peptide (a short chain of amino acids) that copies what the hunger hormone ghrelin does: it tells the body to release a quick, short burst of growth hormone (GH). Small human studies in the 1990s showed it does this dependably. But every one of those trials was tiny, brief,…

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Tesamorelin

Tesamorelin, sold as Egrifta, is one of the few peptides in this space that actually has strong, FDA-grade human evidence behind it. The catch: almost all of that evidence comes from one specific group of patients. And a lot of the way the compound gets marketed elsewhere goes well past what those…

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