Compare · GH secretagogue
Hexarelin vs Tesamorelin
Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.
| Hexarelin | Tesamorelin | |
|---|---|---|
| Evidence | Preliminary human | Strong human |
| Class | GH secretagogue | GH secretagogue |
| Summary | A synthetic ghrelin-mimicking peptide that reliably spikes growth hormone in small studies, but was never approved and is banned in sport. | Tesamorelin is an FDA-approved GHRH analogue with solid RCT evidence for shrinking visceral fat in HIV-associated lipodystrophy, but little proof outside that group. |
| Full profile → | Full profile → |
Hexarelin
Hexarelin is a synthetic peptide that mimics the hunger hormone ghrelin to provoke a sharp, short-lived burst of growth hormone (GH). Small human studies in the 1990s showed it does this reliably, but every trial was tiny, brief, and measured surrogate markers rather than real-world outcomes. It…
Tesamorelin
Tesamorelin, sold as Egrifta, is one of the few peptides in this space with genuine, FDA-grade human evidence behind it. The catch is that the evidence is almost entirely confined to one specific medical population, and a lot of how the compound is marketed elsewhere goes well beyond what those…