Compare · GH secretagogue
Hexarelin vs Sermorelin
Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.
| Hexarelin | Sermorelin | |
|---|---|---|
| Evidence | Preliminary human | Preliminary human |
| Class | GH secretagogue | GH secretagogue |
| Summary | A synthetic ghrelin-mimicking peptide that reliably spikes growth hormone in small studies, but was never approved and is banned in sport. | Sermorelin is a synthetic GHRH fragment that nudges the pituitary to release growth hormone; human data is old and thin, with no modern anti-aging RCTs. |
| Full profile → | Full profile → |
Hexarelin
Hexarelin is a synthetic peptide that mimics the hunger hormone ghrelin to provoke a sharp, short-lived burst of growth hormone (GH). Small human studies in the 1990s showed it does this reliably, but every trial was tiny, brief, and measured surrogate markers rather than real-world outcomes. It…
Sermorelin
Sermorelin is one of the oldest peptides in the "growth hormone" category, and unlike most of its peers it once held FDA approval. That history is often used to imply more about its benefits than the evidence supports.