Compare · GH secretagogue
Hexarelin vs MK-677
Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.
| Hexarelin | MK-677 | |
|---|---|---|
| Evidence | 6/10 | 7/10 |
| Class | GH secretagogue | GH secretagogue |
| Summary | A synthetic ghrelin-mimicking peptide that reliably spikes growth hormone in small studies, but was never approved and is banned in sport. | MK-677 reliably raises growth hormone and IGF-1, but disease trials failed and one was stopped for a heart-failure signal. Investigational, never approved. |
| Full profile → | Full profile → |
Hexarelin
Hexarelin is a lab-made peptide (a short chain of amino acids) that copies what the hunger hormone ghrelin does: it tells the body to release a quick, short burst of growth hormone (GH). Small human studies in the 1990s showed it does this dependably. But every one of those trials was tiny, brief,…
MK-677
MK-677, also called ibutamoren, is one of the odder entries you'll find in any peptide reference — because it isn't actually a peptide. It's a man-made molecule that tricks the body into releasing more of its own growth hormone. And unlike most of the products sold to the fitness and "anti-aging"…