Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · GH secretagogue

Hexarelin vs Ipamorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

HexarelinIpamorelin
Evidence 6/10 6/10
ClassGH secretagogueGH secretagogue
SummaryA synthetic ghrelin-mimicking peptide that reliably spikes growth hormone in small studies, but was never approved and is banned in sport.A selective growth-hormone-releasing peptide with early human safety data but a failed efficacy trial; never approved and banned in sport.
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Hexarelin

Hexarelin is a lab-made peptide (a short chain of amino acids) that copies what the hunger hormone ghrelin does: it tells the body to release a quick, short burst of growth hormone (GH). Small human studies in the 1990s showed it does this dependably. But every one of those trials was tiny, brief,…

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Ipamorelin

Ipamorelin is a lab-made peptide (a short chain of amino acids, the building blocks of proteins) that briefly nudges up your body's growth hormone (GH). It has been tested in people, but the one trial that checked for a real-world health benefit didn't pan out, and it has never been approved for…

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