Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · GH secretagogue

GHRP-6 vs Tesamorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

GHRP-6Tesamorelin
Evidence 6/10 8/10
ClassGH secretagogueGH secretagogue
SummaryAn old growth-hormone-releasing peptide that reliably raises GH and appetite in humans, but whose marketed muscle, fat-loss, and disease claims lack solid trials.Tesamorelin is an FDA-approved GHRH analogue with solid RCT evidence for shrinking visceral fat in HIV-associated lipodystrophy, but little proof outside that group.
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GHRP-6

GHRP-6 is one of the oldest lab-made peptides designed to nudge the body into releasing growth hormone. The basics of what it does in people are genuinely well understood: it raises growth hormone (GH, a hormone that helps the body grow and repair tissue), and it makes people hungry. What is…

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Tesamorelin

Tesamorelin, sold as Egrifta, is one of the few peptides in this space that actually has strong, FDA-grade human evidence behind it. The catch: almost all of that evidence comes from one specific group of patients. And a lot of the way the compound gets marketed elsewhere goes well past what those…

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