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Compare · GH secretagogue

GHRP-6 vs Tesamorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

GHRP-6Tesamorelin
Evidence Preliminary human Strong human
ClassGH secretagogueGH secretagogue
SummaryAn old growth-hormone-releasing peptide that reliably raises GH and appetite in humans, but whose marketed muscle, fat-loss, and disease claims lack solid trials.Tesamorelin is an FDA-approved GHRH analogue with solid RCT evidence for shrinking visceral fat in HIV-associated lipodystrophy, but little proof outside that group.
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GHRP-6

GHRP-6 is one of the oldest synthetic growth-hormone-releasing peptides, and its basic pharmacology in humans is genuinely well understood: it raises growth hormone (GH) and it makes people hungry. What is missing is the part that actually matters for the claims attached to it. For muscle growth,…

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Tesamorelin

Tesamorelin, sold as Egrifta, is one of the few peptides in this space with genuine, FDA-grade human evidence behind it. The catch is that the evidence is almost entirely confined to one specific medical population, and a lot of how the compound is marketed elsewhere goes well beyond what those…

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