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Compare · GH secretagogue

GHRP-6 vs Sermorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

GHRP-6Sermorelin
Evidence Preliminary human Preliminary human
ClassGH secretagogueGH secretagogue
SummaryAn old growth-hormone-releasing peptide that reliably raises GH and appetite in humans, but whose marketed muscle, fat-loss, and disease claims lack solid trials.Sermorelin is a synthetic GHRH fragment that nudges the pituitary to release growth hormone; human data is old and thin, with no modern anti-aging RCTs.
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GHRP-6

GHRP-6 is one of the oldest synthetic growth-hormone-releasing peptides, and its basic pharmacology in humans is genuinely well understood: it raises growth hormone (GH) and it makes people hungry. What is missing is the part that actually matters for the claims attached to it. For muscle growth,…

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Sermorelin

Sermorelin is one of the oldest peptides in the "growth hormone" category, and unlike most of its peers it once held FDA approval. That history is often used to imply more about its benefits than the evidence supports.

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