Compare · GH secretagogue
GHRP-6 vs MK-677
Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.
| GHRP-6 | MK-677 | |
|---|---|---|
| Evidence | 6/10 | 7/10 |
| Class | GH secretagogue | GH secretagogue |
| Summary | An old growth-hormone-releasing peptide that reliably raises GH and appetite in humans, but whose marketed muscle, fat-loss, and disease claims lack solid trials. | MK-677 reliably raises growth hormone and IGF-1, but disease trials failed and one was stopped for a heart-failure signal. Investigational, never approved. |
| Full profile → | Full profile → |
GHRP-6
GHRP-6 is one of the oldest lab-made peptides designed to nudge the body into releasing growth hormone. The basics of what it does in people are genuinely well understood: it raises growth hormone (GH, a hormone that helps the body grow and repair tissue), and it makes people hungry. What is…
MK-677
MK-677, also called ibutamoren, is one of the odder entries you'll find in any peptide reference — because it isn't actually a peptide. It's a man-made molecule that tricks the body into releasing more of its own growth hormone. And unlike most of the products sold to the fitness and "anti-aging"…