Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · GH secretagogue

GHRP-6 vs Ipamorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

GHRP-6Ipamorelin
Evidence 6/10 6/10
ClassGH secretagogueGH secretagogue
SummaryAn old growth-hormone-releasing peptide that reliably raises GH and appetite in humans, but whose marketed muscle, fat-loss, and disease claims lack solid trials.A selective growth-hormone-releasing peptide with early human safety data but a failed efficacy trial; never approved and banned in sport.
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GHRP-6

GHRP-6 is one of the oldest lab-made peptides designed to nudge the body into releasing growth hormone. The basics of what it does in people are genuinely well understood: it raises growth hormone (GH, a hormone that helps the body grow and repair tissue), and it makes people hungry. What is…

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Ipamorelin

Ipamorelin is a lab-made peptide (a short chain of amino acids, the building blocks of proteins) that briefly nudges up your body's growth hormone (GH). It has been tested in people, but the one trial that checked for a real-world health benefit didn't pan out, and it has never been approved for…

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