Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · GH secretagogue

GHRP-2 vs Tesamorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

GHRP-2Tesamorelin
Evidence 6/10 8/10
ClassGH secretagogueGH secretagogue
SummaryGHRP-2 (pralmorelin) provokes a growth hormone pulse. It is an approved diagnostic in Japan, but the human therapeutic and anti-aging evidence is small and old.Tesamorelin is an FDA-approved GHRH analogue with solid RCT evidence for shrinking visceral fat in HIV-associated lipodystrophy, but little proof outside that group.
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GHRP-2

GHRP-2 is one of those compounds with a real but narrow medical use that has been stretched far past what the evidence supports. In Japan it is an approved diagnostic tool: one dose triggers a measurable spike in growth hormone, which helps doctors check whether someone is making too little of it.…

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Tesamorelin

Tesamorelin, sold as Egrifta, is one of the few peptides in this space that actually has strong, FDA-grade human evidence behind it. The catch: almost all of that evidence comes from one specific group of patients. And a lot of the way the compound gets marketed elsewhere goes well past what those…

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