Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · GH secretagogue

GHRP-2 vs Sermorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

GHRP-2Sermorelin
Evidence 6/10 8/10
ClassGH secretagogueGH secretagogue
SummaryGHRP-2 (pralmorelin) provokes a growth hormone pulse. It is an approved diagnostic in Japan, but the human therapeutic and anti-aging evidence is small and old.Sermorelin is a synthetic GHRH fragment that nudges the pituitary to release growth hormone; human data is old and thin, with no modern anti-aging RCTs.
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GHRP-2

GHRP-2 is one of those compounds with a real but narrow medical use that has been stretched far past what the evidence supports. In Japan it is an approved diagnostic tool: one dose triggers a measurable spike in growth hormone, which helps doctors check whether someone is making too little of it.…

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Sermorelin

Sermorelin is one of the oldest peptides in the "growth hormone" group, and unlike most of its cousins it actually held FDA approval at one point. People often lean on that history to suggest it does more than the evidence really backs up.

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