Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · GH secretagogue

GHRP-2 vs Ipamorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

GHRP-2Ipamorelin
Evidence 6/10 6/10
ClassGH secretagogueGH secretagogue
SummaryGHRP-2 (pralmorelin) provokes a growth hormone pulse. It is an approved diagnostic in Japan, but the human therapeutic and anti-aging evidence is small and old.A selective growth-hormone-releasing peptide with early human safety data but a failed efficacy trial; never approved and banned in sport.
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GHRP-2

GHRP-2 is one of those compounds with a real but narrow medical use that has been stretched far past what the evidence supports. In Japan it is an approved diagnostic tool: one dose triggers a measurable spike in growth hormone, which helps doctors check whether someone is making too little of it.…

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Ipamorelin

Ipamorelin is a lab-made peptide (a short chain of amino acids, the building blocks of proteins) that briefly nudges up your body's growth hormone (GH). It has been tested in people, but the one trial that checked for a real-world health benefit didn't pan out, and it has never been approved for…

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