Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · GH secretagogue

GHRP-2 vs Hexarelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

GHRP-2Hexarelin
Evidence 6/10 6/10
ClassGH secretagogueGH secretagogue
SummaryGHRP-2 (pralmorelin) provokes a growth hormone pulse. It is an approved diagnostic in Japan, but the human therapeutic and anti-aging evidence is small and old.A synthetic ghrelin-mimicking peptide that reliably spikes growth hormone in small studies, but was never approved and is banned in sport.
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GHRP-2

GHRP-2 is one of those compounds with a real but narrow medical use that has been stretched far past what the evidence supports. In Japan it is an approved diagnostic tool: one dose triggers a measurable spike in growth hormone, which helps doctors check whether someone is making too little of it.…

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Hexarelin

Hexarelin is a lab-made peptide (a short chain of amino acids) that copies what the hunger hormone ghrelin does: it tells the body to release a quick, short burst of growth hormone (GH). Small human studies in the 1990s showed it does this dependably. But every one of those trials was tiny, brief,…

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