Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · Anabolic steroid

Drostanolone vs Mesterolone

Both are anabolic steroid compounds. Here's how they line up on the evidence — graded the same way.

DrostanoloneMesterolone
Evidence 8/10 1/10
ClassAnabolic steroidAnabolic steroid
SummaryDrostanolone is an injectable, DHT-derived anabolic-androgenic steroid once approved as a palliative breast-cancer drug. Its bodybuilding reputation for 'hardening' and 'dryness' has no controlled human evidence, and it carries the full androgen-class risk profile.Mesterolone is an oral, DHT-derived anabolic-androgenic steroid once sold abroad for male hypogonadism and idiopathic infertility. Controlled human trials for its two historic uses (fertility, mood) are negative or unconvincing, and its performance 'anti-estrogen' reputation has no strong human evidence.
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Drostanolone

Drostanolone, almost always called by its brand name Masteron, is a lab-made anabolic-androgenic steroid (a synthetic version of a male sex hormone, built to grow muscle). It belongs to the dihydrotestosterone (DHT) family — DHT is a potent natural form of testosterone. It was once an FDA-approved…

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Mesterolone

Mesterolone, almost always sold under the brand name Proviron, is a man-made oral steroid. More precisely, it's an anabolic-androgenic steroid (AAS) — a synthetic relative of the male hormone dihydrotestosterone (DHT). It's an androgen (a male-hormone-type drug), not a peptide and not a SARM.…

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