Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · GH secretagogue

CJC-1295 vs Sermorelin

Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.

CJC-1295Sermorelin
Evidence 6/10 8/10
ClassGH secretagogueGH secretagogue
SummaryA long-acting GHRH analog that raises GH and IGF-1 in short human trials, but has no clinical-outcome data, is not FDA-approved, and is banned in sport.Sermorelin is a synthetic GHRH fragment that nudges the pituitary to release growth hormone; human data is old and thin, with no modern anti-aging RCTs.
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CJC-1295

CJC-1295 is a lab-made copy of a natural hormone called GHRH (growth hormone-releasing hormone — the signal that tells your body to make growth hormone). It's built to nudge your body into releasing more of its own growth hormone (GH). Short studies in people confirm it does raise GH and IGF-1 (a…

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Sermorelin

Sermorelin is one of the oldest peptides in the "growth hormone" group, and unlike most of its cousins it actually held FDA approval at one point. People often lean on that history to suggest it does more than the evidence really backs up.

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