Compare · GH secretagogue
CJC-1295 vs MK-677
Both are gh secretagogue compounds. Here's how they line up on the evidence — graded the same way.
| CJC-1295 | MK-677 | |
|---|---|---|
| Evidence | Preliminary human | Preliminary human |
| Class | GH secretagogue | GH secretagogue |
| Summary | A long-acting GHRH analog that raises GH and IGF-1 in short human trials, but has no clinical-outcome data, is not FDA-approved, and is banned in sport. | MK-677 reliably raises growth hormone and IGF-1, but disease trials failed and one was stopped for a heart-failure signal. Investigational, never approved. |
| Full profile → | Full profile → |
CJC-1295
CJC-1295 is a synthetic growth hormone-releasing hormone (GHRH) analog designed to make the body secrete more of its own growth hormone (GH). Short human studies confirm it raises GH and IGF-1, but no trial has shown it changes any health or performance outcome, and no version is FDA-approved.
MK-677
MK-677, also called ibutamoren, is one of the more unusual entries in any peptide reference — because it is not a peptide. It is a synthetic small molecule that fools the body into releasing more of its own growth hormone, and unlike most compounds marketed to the fitness and "anti-aging" crowd, it…