Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

Andarine vs YK-11

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

AndarineYK-11
Evidence 3/10 3/10
ClassSARMSARM
SummaryA non-steroidal SARM with tissue-selective anabolic activity in rodents, but no completed human efficacy trials; clinical development was halted over vision side effects.YK-11 is a synthetic steroidal SARM marketed for muscle growth, but its claimed human benefits rest entirely on cell-culture data — there are no human trials, and it is an unapproved drug banned in sport.
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Andarine

Andarine (S4) is a SARM — a selective androgen receptor modulator (a lab-made molecule designed to act on the body's testosterone-sensing system in a targeted way). It is a synthetic small molecule, not a peptide and not an anabolic steroid. You will often see it sold in fitness, biohacking, and…

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YK-11

YK-11 is a lab-made compound sold as a SARM (selective androgen receptor modulator — a drug designed to switch on the body's muscle-building signals) and pitched as a way to add muscle. The marketing aside, it is not a peptide. It is a steroid-style molecule built on a 19-norandrostane backbone (a…

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