Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

Andarine vs S23

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

AndarineS23
Evidence 3/10 3/10
ClassSARMSARM
SummaryA non-steroidal SARM with tissue-selective anabolic activity in rodents, but no completed human efficacy trials; clinical development was halted over vision side effects.S23 is a synthetic selective androgen receptor modulator (SARM) — not a peptide — studied only in rodents as a male contraceptive candidate. There are no human trials, and it is an unapproved drug banned in sport.
Full profile → Full profile →

Andarine

Andarine (S4) is a SARM — a selective androgen receptor modulator (a lab-made molecule designed to act on the body's testosterone-sensing system in a targeted way). It is a synthetic small molecule, not a peptide and not an anabolic steroid. You will often see it sold in fitness, biohacking, and…

Read the full evidence-graded Andarine profile →

S23

S23 is a lab-made drug in a family called SARMs (selective androgen receptor modulators — molecules that switch on the same cell "docking points" as testosterone, but only in certain tissues). It is not a peptide. The idea behind it was to build up muscle and bone while having relatively little…

Read the full evidence-graded S23 profile →

← All comparisons & the compare tool