Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

Andarine vs Testolone

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

AndarineTestolone
Evidence 3/10 3/10
ClassSARMSARM
SummaryA non-steroidal SARM with tissue-selective anabolic activity in rodents, but no completed human efficacy trials; clinical development was halted over vision side effects.An investigational, non-approved selective androgen receptor modulator (SARM) with no published human efficacy evidence for fitness use, a documented serious liver-injury case, and prohibited status in sport.
Full profile → Full profile →

Andarine

Andarine (S4) is a SARM — a selective androgen receptor modulator (a lab-made molecule designed to act on the body's testosterone-sensing system in a targeted way). It is a synthetic small molecule, not a peptide and not an anabolic steroid. You will often see it sold in fitness, biohacking, and…

Read the full evidence-graded Andarine profile →

Testolone

Testolone (RAD-140) is a selective androgen receptor modulator, or SARM (a drug that switches on the body's testosterone-sensing receptor in a targeted way). It is a small molecule made in a lab — not a peptide, and not an anabolic steroid. It was created as an experimental drug, was never approved…

Read the full evidence-graded Testolone profile →

← All comparisons & the compare tool