Independent reference & toolkit 100 compounds graded · Last reviewed June 2026

Compare · SARM

Andarine vs Ostarine

Both are sarm compounds. Here's how they line up on the evidence — graded the same way.

AndarineOstarine
Evidence 3/10 7/10
ClassSARMSARM
SummaryA non-steroidal SARM with tissue-selective anabolic activity in rodents, but no completed human efficacy trials; clinical development was halted over vision side effects.Ostarine is an investigational selective androgen receptor modulator (SARM) — not a peptide — with real but limited human evidence for lean-mass effects, no regulatory approval anywhere, and documented liver-injury and hormone-suppression signals.
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Andarine

Andarine (S4) is a SARM — a selective androgen receptor modulator (a lab-made molecule designed to act on the body's testosterone-sensing system in a targeted way). It is a synthetic small molecule, not a peptide and not an anabolic steroid. You will often see it sold in fitness, biohacking, and…

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Ostarine

Ostarine (also called MK-2866 or enobosarm) is a selective androgen receptor modulator (a compound designed to act like a muscle-building hormone in some tissues but not others). It is often — and wrongly — sold online as a "safer steroid alternative" for building muscle. It is not a peptide, and…

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