Compare · Exercise mimetic
AICAR vs SLU-PP-332
Both are exercise mimetic compounds. Here's how they line up on the evidence — graded the same way.
| AICAR | SLU-PP-332 | |
|---|---|---|
| Evidence | No credible evidence | Animal only |
| Class | Exercise mimetic | Exercise mimetic |
| Summary | AICAR (acadesine) is a small-molecule AMPK activator — not a peptide — famous for making sedentary mice run farther, but with no credible human evidence for endurance, fat loss, or longevity. It is an unapproved experimental drug, banned in sport at all times. | SLU-PP-332 is a synthetic small-molecule pan-agonist of the estrogen-related receptors (ERRα/β/γ) studied as an 'exercise mimetic' — not a peptide, and animal-stage only with no human data. |
| Full profile → | Full profile → |
AICAR
AICAR is a small molecule sold online as an "exercise in a pill." It is not a peptide, not a hormone, and not a SARM — it is an AICA-riboside that activates the metabolic enzyme AMPK. Its entire reputation rests on a 2008 mouse study showing that sedentary animals given AICAR ran substantially…
SLU-PP-332
SLU-PP-332 is a synthetic small molecule sold and discussed in the "research chemical" market as an "exercise mimetic" — a compound meant to trigger some of the metabolic effects of exercise without physical training. Despite often being grouped with peptides online, it is not a peptide: it is a…